Could Our Microbiome Treat Mental Disease and Other Illnesses

Could Our Microbiome Treat Mental Disease and Other Illnesses

The possible healing properties of our poop.

We are always looking for innovative new treatments, from immunotherapy to gene therapy to novel antibiotics. But what if we had innovative new treatments inside our own body, namely our gut bacteria?

What if some people’s gut bacteria could be used for treating other people’s diseases?

It has happened in the past.

The past and present use of people’s microbiome (a sophisticated name for bugs in people’s poop).

In the 4th century in China, medical doctor Ge Hong created a new treatment for diarrhea. It was called “yellow soup” and was a broth made with… not lemons, not yellow bell peppers, but the poop of a healthy person.

I can imagine you, reader, grimacing. Yet, this “yellow soup” worked very well in treating diarrhea.

More recently, when people are exposed to long antibiotic treatments, not only are the culprit bugs destroyed, but all their good bacteria are destroyed too. As a result, some people’s guts are colonized by a very-difficult-to-treat bug called Clostridium Difficile (C. Diff.) and despite additional antibiotic treatments, these patients sometimes develop recurrent C. Diff. infections.

Since no other treatment can kill these recurrent infections all of the time, some physicians try to use healthy people’s poop, sometimes using the sexual partner’s poop to treat the infected person (used as an enema). And—surprise!—the partner’s poop often cures the infected person.

Dr. Jessica Allegreti from Harvard University mentions in Harvard Health Publishing that Fecal Microbiota Transplants (FMT) have a cure rate of 80 to 90 percent with very often only a single treatment in cases of recurrent C. Diff. infections.

How FMTs work their magic isn’t yet explained, but one theory is that “healthy” bugs in our guts may secrete bactericidal compounds that kill C. Diff. Another theory postulates that when healthy bugs are restored through a transplant, they outcompete C. Diff. for nutrients.

But what if FMTs (and the bugs contained in people’s poop) could be used to treat diseases other than C. Diff. infections?

What if FMTs could be used to treat Crohn’s disease or recurrent urinary tract infections? What if FMTs could treat mental illness, Alzheimer’s disease, Parkinson’s disease, autism, and even obesity? What if FMTs could work against cancer?

What could be the future use of people’s microbiome (contained in people’s poop)?

At the beginning of December this year, my husband and I interviewed Dr. Sabine Hazan, gastroenterologist, founder, and CEO of Progenabiome in Ventura, California, and Dr. Brad Barrows, the medical director of the company. Dr. Hazan conducts research and leads clinical trials on the microbiome and FMTs.

Chris Gilbert, MD, PhD
Dr. Sabine Hazan and Dr. Brad Barrows
Source: Chris Gilbert, MD, PhD

Dr. Hazan has done 150 clinical trials in the last 15 years. She explained that we have in our gut up to 100 trillion microbes and that there are more than 150,000 species of them—some well-known, others not so well-known.

Dr. Hazan’s theory is that, just like Penicillin was discovered from the growth of mold, all gut bacteria, gut fungi, and viruses might have properties that have yet to be discovered.

She is currently analyzing the gut microbiome of people with chronic fatigue syndrome, chronic constipation, celiac disease, Crohn’s disease, ulcerative colitis, recurrent urinary tract infections, psoriasis, Lyme’s disease, Alzheimers’s disease, Parkinson’s disease, autism, colorectal cancer, obesity, and several other conditions. In doing so, Dr. Hazan is discovering that patients with certain diseases have a very different gut microbiome than people without any disease.

But first let’s take a look at what a microbiome looks like, from Dr. Hazan’s point of view:

Below is a chart that shows the microbiome of 26 randomly selected individuals. In the chart, each column represents a different individual and each color represents a different species of bug. See how complex every microbiome is?

Could Our Microbiome Treat Mental Disease and Other Illnesses
The microbiome of 26 randomly selected individuals
Source: Used with permission of Dr. Sabine Hazan

Now let’s look at families.

Below is the microbiome of one family:

Could Our Microbiome Treat Mental Disease and Other Illnesses
Microbiome of one family: Father, mother and two children (in separate columns from left to right).
Source: Used with permission from Dr. Sabine Hazan

See how the colors are kind of similar between father, mother and the two children? This means they have the same species of bugs in their guts.

Why is that?

Could it be that they are genetically related? But what about the mother and father who are not genetically related? Could it be because they kiss and have sex? Could it be because they eat the same kind of food or because they live in the same house?

All of these possibilities are likely.

Now compare the above family microbiome with the family microbiome below:

Could Our Microbiome Treat Mental Disease and Other Illnesses
Family with one autistic daughter: mother, daughter 1 and daughter 2 (in separate columns from left to right).
Source: Used with permission from Dr. Sabine Hazan

This second family has a very different microbiome than the first, which means that they have very different sets of bugs in their guts.

In this second family—mother, daughter 1 and daughter 2‚ one of the daughters has autism. Can you guess, just by looking at the microbiome, which one has autism?

It is the one in the middle, daughter 1.

Do you notice how different the microbiome of daughter 1 is from the rest of the family? It seems that it has too much of a certain bacteria (the one in green in the middle) and misses a lot of variety of gut bacteria, one of them being Bifidobacter.

Moreover, there is less diversity (number of different organisms in daughter 1) indicating that her microbiome is much less balanced than that of her mother or sister.

What is Dr. Hazan’s plan for the future?

Dr. Hazan’s plan is to understand the role of the microbiome in diseases and to use her findings to help her colleagues perfect the area of fecal transplant. Most importantly, she wants to shed some light on the mechanism of why fecal transplant helps improve a disease or cures Clostridium Difficile.

Dr. Hazan doesn’t believe in one pill fits everyone, nor should a probiotic fit everyone. She believes in precision medicine and individuality as well as the need to remain diversified.

“The one thing we learned from the microbiome analysis is that a healthy microbiome is one that is diverse in its microbial composition,” Dr. Hazan says.

She hopes to work with the FDA to organize a trial on autistic children using the data she gathered from microbiome analysis.

Has Dr. Hazan seen any positive results for any diseases other than Clostridium Difficile infections?

Yes, she has.

Through the mentorship of Dr. Thomas Borody, a leader in fecal transplantation, Dr. Hazan is applying methods and protocols to use FMT in a clinical trial on patients with Crohn’s disease, transplanting them with the microbiome of healthy individuals. Her results will be published soon. She has also seen improvement in one case of Alzheimer’s dementia and one case of chronic urinary tract infection.

Other physicians have had some great results too.

Dr. Moayyedi from McMaster University in Ontario, Canada, performed Fecal Microbiota Transplantations on 38 patients suffering from ulcerative colitis. Nine of Moayyedi’s patients went into remission and were able to stop all treatments (the results were published in the Journal of Gastro-Enterology in 2015).

Dr. Johnsen from Harstad University Hospital in Norway performed Fecal Microbiota Transplantations on patients suffering from Irritable Bowel Disease (IBS) and had 65 percent of patients improved—much better than placebo (these results were published in the Lancet in 2018).

So, could FMTs be the new treatment of choice for many diseases in the future?

We don’t know yet, but as Dr. Thomas Borody says: “It takes courage and years of perseverance to change paradigms.” Dr. Borody is presently working on a protocol on FMT and Parkinson’s disease.

We need more clinical trials on larger samples of patients.

The key will be to find the right Fecal Microbiota Transplant donor to treat each condition and to better assess the risks versus benefits of Fecal Transplant in the future.

In the meantime, here are more questions you may have about FMTs:

How are FMTs done?

Some people put the FMT in capsules to be taken orally, but stomach and bile acids might destroy the therapeutic microbiota if taken this way. Thus, gastroenterologists like to transplant gut bacteria via enemas or place them directly near the caecum via a colonoscopy.

How risky are FMTs?

We don’t know yet. All that we know is that the risks are not zero.

One person died after an FMT in 2019, but that individual had leukemia and a severely weakened immune system, and the donor had E. Coli bacteria that were resistant to antibiotics.

Since then, donors have been better selected.

Can FMTs reverse obesity?

Can poop be taken from a slim person and placed in the colon of an obese person so that the microbiota of the slim person take over?

Well, the answer is yes… in rats. Maria Guirro and colleague from Rovira University in Spain (the study was published in PLoS One 2019) showed that transplanting gut bacteria from lean rats to obese rats created a change in the obese rats gut bacteria, making the obese rats’ gut bacteria similar to the ones from the lean rats and thus less able to harvest energy from food.

Clinical trials with humans are starting (see in references below).

What can we take away from all this?

One thing is for sure: Depending on what we eat, drink and how much stress we have in our life, our microbiome changes and those changes can trigger diseases.

An example is that stress makes our stomach, liver, and gallbladder secrete more acid, and those acids will kill a lot of our good bacteria, creating an imbalance in our gut flora.  On the other hand, eating yogurt will provide us with good bacteria, but too much sugar in our diet will create a growth of bad bacteria, creating another kind of imbalance and triggering other diseases.

So, let’s be aware that we are not alone in our bodies. We are the host of trillions of friends living in our gut that help us remain healthy. Let’s be good hosts and keep our microbiome balanced by eating less processed foods, less sugar and having less stress in our life.

Because after all, the future might really be in our poop… no sh*t!

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The gut microbiome in health and disease

The gut microbiome in health and disease

Here is something that will change healthcare and make us more aware of our gut microbiome

This data will change healthcare and make us more aware of our gut microbiome

Progenabiome, a physician-owned genetic sequencing laboratory, found cutting-edge data on Clostridium difficile (C.diff), a disease burdening 500,000+ Americans yearly. They will present a validated, verified, and reproduced C.diff Assay at The American College of Gastroenterology (ACG) 2019 Annual Scientific Meeting on Monday, Oct. 28, 2019 in San Antonio.

Progenabiome, a genetic sequencing laboratory of the gut flora. Leading the way into the FUTURE by understanding the microbiome NOW. The quest for a new healthcare revolution!
Progenabiome, a genetic sequencing laboratory of the gut flora. Leading the way into the FUTURE by understanding the microbiome NOW. The quest for a new healthcare revolution!

“This data will change healthcare and make us more aware of our gut microbiome,” said Dr. Sabine Hazan-Steinberg, CEO and Founder of Progenabiome. “2500 years later, we’re proving Hippocrates right…everything starts in the gut.”

Dr. Hazan, a Malibu-based gastroenterologist, has 20+ years experience leading clinical trials, many for C.diff. When trials failed, she used fecal microbiota transplant (FMT), following advice from friend Dr. Neil Stollman, gastroenterologist at UCSF and East Bay Center for Digestive Health. She also followed great work by Dr. Thomas Borody, FMT pioneer and Centre for Digestive Diseases founder. Success post-FMT for recurrent C.diff suggested the microbiome holds many answers.

Knowing the C.diff microbe has existed for 10 million years, she questioned why it now takes 50,000 lives annually.

Dr. Sydney Finegold, infectious disease specialist who researched Autism/microbiome for 50 years, recommended she acquire a next-generation sequencer. When he passed in 2018, his books went to Hazan, hoping she could continue his legacy.

In January, she joined pathologist Dr. Brad Barrows and scientific director Dr. Andreas Papoutsis to launch Progenabiome. Their first run found non-toxigenic C.diff in every sample, including those not diagnosed with the disease. Preliminary data shows the C.diff microbe is not transmitted hand-to-mouth as previously believed. It is already in the gut and becomes toxic when something ingested triggers it.

Progenabiome will present this groundbreaking discovery at ACG 2019 (Poster 1027 / Booth 1931) and the 7th Annual International C.diff Conference November 6-7, 2019 in St. Louis.

Progenabiome is investigating the role of the gut flora in various diseases through 11 studies overlooked by New England IRB. Progenabiome’s Mission: to better understand, prevent, and treat diseases by analyzing specific genetic codes of 40 trillion gut microbes. Dr. Hazan believes the art of Medicine lies in our ability to see outside the box and recognize that all microbes and humans are unique.

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Contact: Stephanie Davis,



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4 Proven Local SEO Tips to Rank High in

Hey everyone it’s neil patel here for another Q&A Thursday video I’m here with Adam from viewership hello everyone and this week’s question is we have this one from Carson and his question for you is how does one go about ranking high SEO for search terms including near me with Geographic relevance for this example dog trainers near me I’m assuming he’s a dog trainer yeah so near me means anytime you do a search like plumbers near me dog trainers near me whatever it may be like gardener near me right there including that term near me in the Google search so what he’s asking is how can I rank my business when people are typing in whatever term plus near me so the first thing you need to do whatever you want to rank for google it type in that plus near me and you’ll see all the localized sites that Google is pulling from for those near me listings make sure you’re listed there by getting listed there it helps tremendously because if they’re pulling from those sites and you’re there there’s a higher chance that you’re gonna get listed you live in Boston right so let’s use the example of Boston the next if we have is you want to make sure you’re listing the local landmarks town lines as well as old school like driving directions to wherever that you’re servicing so on your website in Boston there’s probably a lot of suburbs in Boston

correct yeah and what are some of them Charlestown Cambridge so on your website you want to list all the little subsections of Boston or whatever city you’re servicing all the landmarks all the town lines because they could be all close to each other and you even want to go as far as putting the localized old-school directions from how people get to get to wherever they are to you by doing that you’re gonna be much better off in getting more traffic you also want to make sure you have a localized number everyone’s like oh you want a 800 number or 888 number but no you want to localize numbers so people know that you’re there you’re in person and you’re not one of those you know sites that has near me listings for every single city in the United States and they’re not really near there you know the a hundred place first looks like ours that’s like the whole thing I was looking for a flower shop near medium bossed I lived downtown I ended up going like way outside of town to find a place that was like a legit local place not an 800 flowers or anything like that so good advice yeah she just called Amex Amex deals with all that for you they’re really official that’s really corporate there’s so much for that no but and this will find the local

flower shop for you oh nice yeah yeah you should try that out good little tip so in addition to that when people go look for services near them whether it’s plumbing dog sitting dog walking they also check out your overall company or you and how you’re doing overall so they may go to Yelp in those national services to type in your name to see how many reviews you have and if your legitimate so make sure you ask people who have a good experience to leave a review on whatever site whether it’s Google or whether of it’s you know on Yelp or whatever it may be because it helps create legitimacy because even if you’re not ranking at the top by having more reviews people be like oh wow you got five or six hundred reviews we’re more likely list you when you do a search google has a local pack and let’s say they pick three listings and the number one spot has ten reviews and number two spot has seven reviews and you’re the third spot if you get a ton of reviews

and now you have 50 or 100 reviews what you’ll find is a lot of people will click on the listing with more reviews and they click on you more than the other two eventually will will push the other two down and push you above them so follow those tips you’ll get way more traffic for people looking for your business or your service near you definitely and I should say that the very fact that you’re watching this is a local business sets you so far apart than all the other local businesses so just know like you’re already killing it just by like following a few of these tips whether you’re watching this or you’re doing something that’s huge because when I talk to most localized businesses they’re like yeah we get our business from word of mouth but we hand out flyers to community businesses around us and I’m like alright there’s an internet there’s phone like yes you should still do those offline tactics we should also use digital tactics as well so thank you guys for watching if you have a comment or a question leave it below I’ll be there to answer and we may choose your question for next week’s Q&A Thursday video and also if you have a local business just want to comment below tell this is an awesome community of people who are like really trying to get it all together so tell us a little bit about the businesses one yeah love to help you out as well thank you for watching make sure you subscribe share tell your friends about us thank you very much

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How to Get More Music Exposure & Sales on Youtube

Hey Angela Carter here with earn money with Angela calm your music success coach and I wanted to wrap up this week this week all this week on this channel we’ve been talking about music marketing on a budget if you’ve missed out you want to make sure that you go back to the videos on this channel we talked about on Monday I believe how to get your music exposed in front of a thousand people for only $5 I did a video this week on how to promote your live local music shows on facebook for free and so we’re wrapping up today Friday it’s the

weekend we’re wrapping up with a video on how to actually use YouTube to get exposure for free but I’m also going to talk about two big mistakes that I see musicians make where they’re leaving money on the table okay so let’s talk about YouTube YouTube is a great way for you to get your music exposed and from a lot of people in fact I know that for me when I first got started online I’ve sold a little bit but my back my background one of the reasons why I’m passionate about helping musicians be able to learn and tap into marketing online is because I’ve sold stuff online before I’m kind of a unique I guess music marketer and the fact that I have had experience and marketing and selling stuff online and I’ve helped other people sell stuff online and one of the the major mediums that I used was video I’ve gotten over 10,000 views to some of my videos I think the the most viewed video I’ve ever done online has been now over 30,000 views so I know how to get exposure on YouTube and I know how to help other people get exposure on YouTube I’ve helped other people get thousands of views on their videos but not only get views and exposures but sell stuff online so one of the things that I see that a lot of musicians one of the mistakes that I see a lot of musicians make there’s two the first one I want to talk about is where

they’re not providing a link to their web where people can learn more too in their YouTube video description if you’ve ever got our YouTube look at right now I’m go to the video description of this video you’ll see my website and what I see is that musician either do one of two things they either don’t put their website there or secondly they put their website there but it’s not clickable meaning on YouTube you have to put the the full URL the full website address in that description to make it clickable and what you want to do is you want to make it easy for people to actually go to your website it’s much much easier to tell people hey just click on the link in the description box below to go to this website as opposed to saying here go to WWE you know earn money with Angela’s com it’s easy for people to just click on a link you want to make it easy for people to do the action that you want them to do if you want them to go to your website to buy your music make it easy you know reminded of my mentor and my leader she just made seventy thousand dollars last month let’s talk about that but anyway she was sharing this story about how when she first got started in her

business she was selling a book from a book that she had from a table at an event one of her friends invited her along to this event that he was doing he had a table at this event he said hey you know you can come along and sell your book at this event well anyway she sold this book at this event and this guy comes up to the table and he says I want to buy your book and she’s okay well you know it’s I forgot how much it was let’s just say $12 so it’s $12 and so he says well okay I have a current I have this credit card here you go and she said oh I’m sorry you know I was invited to this event at the last minute I don’t have a credit card processing machine I would need cash and he said well I have this credit card she’s like well I don’t have a credit card processing machine and he said let me tell you a piece of advice don’t ever make it hard for people to buy from you and he said look well here’s what I’m gonna do I want your book I like you I want you I want this book I’m going to leave you I’m gonna write down my credit card information I’m leaving my credit card and I’m gonna get this book you go figure out a way to process my credit card and he walks away so she’s like scrambling everywhere now trying to figure out how how do i process this car and so she was telling other people this story but I had this guy just came up to me and gave me his credit card information and then it acts like well who the actual

description who is this guy and what does he look like so she described the guy and the people told her at this event well that’s Mark Hoverson he’s a millionaire she’s like what and she said till this day she has never forgotten that what he said so here’s the advice of a millionaire right now don’t ever make it hard for people to buy from you so when you’re on YouTube and you’ve done this great music video you’ve uploaded it don’t ever make it hard for people to learn and where to get access to buy your stuff make it easy put your URL to your website make it clickable so they can click on it in your YouTube video description otherwise you are leaving money at the table like my leader like my mentor did learn from a millionaire second thing that I’m second mistake that I see people make on YouTube especially musicians is they’ll put a youtube video up and then they just leave it there and they think that that’s going to magically now bring all these views that’s not how it works here’s what I tell people it’s a strategy that’s really really easy it’s called peep the game we’re gonna mean by that look at what other people are doing especially what other musicians are doing to get their music out there and get exposure learn from successful people watch what they do so when you see a musician let’s talk about like a really popular musician when you see a musician watch and release a new video for maybe their latest

single what do they do they they go out and they promote it they don’t just do the video and then just okay we’ve did this video and we’re just gonna just leave it you know here they go out and they they promote it how they put it on YouTube VEVO is a really popular channel now and they do it you know through VEVO they syndicated through VEVO we call it syndication I’m talking about that wording a little bit here they go on television shows they go on different networks and they perform the show like if you look at a lot of popular R&B artists or rap artists they not only release their single where they go they go to 106 apart to release the video to promote it or they go perform I want to see the part they go perform on all these different shows there’s artists I mean other genres they go to Good Morning America they go to a Today Show they go out and they promote that stuff they go promote their new single their new video saying that you want to do peep the game see what other successful people are doing and do the same thing when you upload a video to YouTube now you go and promote it your job is not done when you upload it you go and promote that video tweet it that’s what major artists do all the time they say hey they tell their following hey I just released this new video check it out you do the same thing go to Twitter go to Facebook those are your networks you know how I said you

know the the popular artists go to you know Good Morning America Today Show 106 apart Tiare all these different places then you have your own network you know what they’re called LinkedIn they call it Facebook they call it Twitter you have your own network YouTube go out and promote that piece that video go and promote it so that’s the Ellen I said I want to talk about syndication we call that syndication when you release a piece of content online and you go and promote it could be a blog post it could be you know you just got interviewed on a radio internet radio show you go out and you promote it and you we call it’s indicating meaning putting it in different places put that same piece of content that your YouTube video and put it in on different networks in different networks to expose it to different places that you do this and you see this happen all the time with television shows like for example Fresh Prince of Bel Air’s one of my favorite shows from childhood right well the reruns still show they back you

know I don’t know when it I think was in the early 90s right when a freshness of bel-air started they had original episodes that they did but now they syndicated it’s called it’s in syndication meaning now those you know original shows are now being reran reruns are being shown on different networks I know TBS I think shows a lot of the old Fresh Prince of bel-air episodes so now they took what they had already produced and they’re syndicating it on different networks people that already have a following right TBS already has a lot of viewers it has a large audience and so that’s what you want to do take what you’ve already produced your video and now go out and spread it on networks that I already have audience you already know how to do this if you peep the game look at what successful so that’s what people are doing and do the same thing this is going to conclude our music marketing on a budget series hope you enjoy it look if you want to learn internet marketing if you want to master how to use the internet to market your music but if you want to learn how to make money on line promoting and marketing your music go to wwm with Angela comm or click on the description the video description a box below click on the link there in

that video description box and learn how to finally utilize the internet to market and get your music exposed to thousands of people and if you want to actually earn money while you learn internet marketing so that maybe you can you know be able to invest in the music that you want maybe you want a studio you want to be able to earn enough to make a studio so that you can the record in music maybe you want to earn enough money to be able to walk away from your job so you can do your music full-time you could also learn how to do that as well I want earn money with Angela comm get started putting your email address on that page watch the video to learn how to make money online but also make sure that you get plugged in to partner with me when you do you’ll get a welcome email from my assistant welcoming you to the team and giving you some instructions on how to plug into our training site so you can get access to learning all this information about internet marketing simplified away and then also you’ll get instructions on how to do and get a phone strategy session with me where we can look at what your goals are your income goals how much money you want to make doing your music marketing your music and help you set up an action plan of how to actually get to your income goals so again go to earn money with Angela’s calm I’m sure that you’ve gotten so much value out of our music marketing on a budget series stay tuned the next week for some more information and some more tips and advice that can help you get your music out there in a big way bye you

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Why the best hire might not have the perfect resume | Regina Hartley

Your company launches a search for an open position. The applications start rolling in, and the qualified candidates are identified. Now the choosing begins. Person A: Ivy League, 4.0, flawless resume, great recommendations. All the right stuff. Person B: state school, fair amount of job hopping, and odd jobs like cashier and singing waitress. But remember — both are qualified. So I ask you: who are you going to pick? My colleagues and I created very official terms to describe two distinct categories of candidates. We call A “the Silver Spoon,” the one who clearly had advantages and was destined for success. And we call B “the Scrapper,” the one who had to fight against tremendous odds to get to the same point. You just heard a human resources director refer to people as Silver Spoons and Scrappers — (Laughter) which is not exactly politically correct and sounds a bit judgmental.

But before my human resources certification gets revoked — (Laughter) let me explain. A resume tells a story. And over the years, I’ve learned something about people whose experiences read like a patchwork quilt, that makes me stop and fully consider them before tossing their resumes away. A series of odd jobs may indicate inconsistency, lack of focus, unpredictability. Or it may signal a committed struggle against obstacles. At the very least, the Scrapper deserves an interview. To be clear, I don’t hold anything against the Silver Spoon; getting into and graduating from an elite university takes a lot of hard work and sacrifice. But if your whole life has been engineered toward success, how will you handle the tough times? One person I hired felt that because he attended an elite university, there were certain assignments that were beneath him, like temporarily doing manual labor to better understand an operation.

Eventually, he quit. But on the flip side, what happens when your whole life is destined for failure and you actually succeed? I want to urge you to interview the Scrapper. I know a lot about this because I am a Scrapper. Before I was born, my father was diagnosed with paranoid schizophrenia, and he couldn’t hold a job in spite of his brilliance. Our lives were one part “Cuckoo’s Nest,” one part “Awakenings” and one part “A Beautiful Mind.” (Laughter) I’m the fourth of five children raised by a single mother in a rough neighborhood in Brooklyn, New York. We never owned a home, a car, a washing machine, and for most of my childhood, we didn’t even have a telephone. So I was highly motivated to understand the relationship between business success and Scrappers, because my life could easily have turned out very differently. As I met successful business people and read profiles of high-powered leaders, I noticed some commonality. Many of them had experienced early hardships, anywhere from poverty, abandonment, death of a parent while young, to learning disabilities, alcoholism and violence.

The conventional thinking has been that trauma leads to distress, and there’s been a lot of focus on the resulting dysfunction. But during studies of dysfunction, data revealed an unexpected insight: that even the worst circumstances can result in growth and transformation. A remarkable and counterintuitive phenomenon has been discovered, which scientists call Post Traumatic Growth. In one study designed to measure the effects of adversity on children at risk, among a subset of 698 children who experienced the most severe and extreme conditions, fully one-third grew up to lead healthy, successful and productive lives.

In spite of everything and against tremendous odds, they succeeded. One-third. Take this resume. This guy’s parents give him up for adoption. He never finishes college. He job-hops quite a bit, goes on a sojourn to India for a year, and to top it off, he has dyslexia. Would you hire this guy? His name is Steve Jobs. In a study of the world’s most highly successful entrepreneurs, it turns out a disproportionate number have dyslexia. In the US, 35 percent of the entrepreneurs studied had dyslexia.

What’s remarkable — among those entrepreneurs who experience post traumatic growth, they now view their learning disability as a desirable difficulty which provided them an advantage because they became better listeners and paid greater attention to detail. They don’t think they are who they are in spite of adversity, they know they are who they are because of adversity. They embrace their trauma and hardships as key elements of who they’ve become, and know that without those experiences, they might not have developed the muscle and grit required to become successful. One of my colleagues had his life completely upended as a result of the Chinese Cultural Revolution in 1966. At age 13, his parents were relocated to the countryside, the schools were closed and he was left alone in Beijing to fend for himself until 16, when he got a job in a clothing factory. But instead of accepting his fate, he made a resolution that he would continue his formal education. Eleven years later, when the political landscape changed, he heard about a highly selective university admissions test.

He had three months to learn the entire curriculum of middle and high school. So, every day he came home from the factory, took a nap, studied until 4am, went back to work and repeated this cycle every day for three months. He did it, he succeeded. His commitment to his education was unwavering, and he never lost hope. Today, he holds a master’s degree, and his daughters each have degrees from Cornell and Harvard. Scrappers are propelled by the belief that the only person you have full control over is yourself. When things don’t turn out well, Scrappers ask, “What can I do differently to create a better result?” Scrappers have a sense of purpose that prevents them from giving up on themselves, kind of like if you’ve survived poverty, a crazy father and several muggings, you figure, “Business challenges? — (Laughter) Really? Piece of cake.

I got this.” (Laughter) And that reminds me — humor. Scrappers know that humor gets you through the tough times, and laughter helps you change your perspective. And finally, there are relationships. People who overcome adversity don’t do it alone. Somewhere along the way, they find people who bring out the best in them and who are invested in their success. Having someone you can count on no matter what is essential to overcoming adversity. I was lucky. In my first job after college, I didn’t have a car, so I carpooled across two bridges with a woman who was the president’s assistant. She watched me work and encouraged me to focus on my future and not dwell on my past. Along the way I’ve met many people who’ve provided me brutally honest feedback, advice and mentorship. These people don’t mind that I once worked as a singing waitress to help pay for college.

(Laughter) I’ll leave you with one final, valuable insight. Companies that are committed to diversity and inclusive practices tend to support Scrappers and outperform their peers. According to DiversityInc, a study of their top 50 companies for diversity outperformed the S&P 500 by 25 percent. So back to my original question. Who are you going to bet on: Silver Spoon or Scrapper? I say choose the underestimated contender, whose secret weapons are passion and purpose. Hire the Scrapper. (Applause) .

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Ten Video Marketing Ideas for Real Estate Agents

10 video marketing ideas for real estate agents and tips on growing your business with YouTube. **** Register for the FREE webinar on how to 10X our business with YouTube here: Want to connect? Reach out on my website here: Learn the best video marketing strategies for growing your business this year on my free 1-hour YouTube masterclass. Watch it here: Sean Cannell on Social Media: FACEBOOK PAGE — I do weekly Facebook Live Streams on this page. QUESTION — Have a question about Online Video, Video Production, Tech, Marketing, or Anything Else? Post in comments section of this video! Check out the complete list of gear I use for creating YouTube videos here: Download the FREE Think Media TV Video Gear Buyer’s guide here: Subscribe to Think Media Here:

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Explore Edmonton Real Estate

Welcome to the number one source for Edmonton homes for sale. Ryan Dutka is proud to offer you this one-stop resource for all of your Edmonton home buying and Edmonton home selling needs. This website provides you with all the latest real estate tools, information, and technology to make your journey the most successful and satisfying undertaking in your real estate adventure. We have carefully developed, and continue to develop, this website to give you the tools and the knowledge to make the most informed decisions with the most up-to-date and relevant facts and figures in the Edmonton real estate market.

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If you’ve ever had to rebuild a #WordPress website then you know that you can easily lose SEO rank. Here are four must-do steps when wanting to avoid an SEO disaster during a website rebuild. Kori Ashton shares tips like content audit, 301 redirects and permalink structure. Find the infographic here… Find the full written tutorial and infographic with links here –… Setting up 301 Redirects –… ********************************************************************* SUBSCRIBE TO FOLLOW KORI –… ********************************************************************* FREE ONLINE COMMUNITY #WordPress Freelancers, Agency Owners & Entrepreneurs can connect in a Slack channel or Facebook Group to discuss business strategies, process improvements, and much more. FROM KORI: Hey Y’all – Thanks for watching. Each week I’m creating videos just like this one to help you improve your online marketing. Be sure to subscribe so that you get access to each video. If you have questions about a process, product, or service that I’ve mentioned in a video, please reach out directly to the authors of that item first. If there’s a question about something specific I’ve shared, comment in the thread and I’ll reply within a day or two.

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Empowering Women In Business To Stand Out From The Rest

I recently had the pleasure of interviewing Amanda Tress, an inspiring female entrepreneur who gives back by empowering women in business. She talks about her path to success, the weight loss program she created, and how she’s been able to make her brand stand out from the rest within the fast-growing, saturated fitness marketplace. When she started her weight loss program three years ago, she received a great deal of negative and hurtful criticism. Back then the idea of intermittent fasting – now a mainstream nutritional tool – was seen as unproven and intimidating to many people. Despite the criticism, Amanda stuck to what she knew to be true from her own results and those of her gym clients. She was able to successfully market her brand, make it stand out from the rest, and build a seven-figure business that continues to grow and thrive. These days, Amanda is empowering women in business with her micro-influencer and train-the-trainer models. The micro-influencers Amanda works with typically have from 3,000 to 10,000 followers. She partners with women in complementary industries, simultaneously helping them make significant income in their own businesses and having them spread the word about her brand. She doesn’t sponsor or compensate these influencers – the endorsements these women give her are genuine. Amanda’s training model also makes her stand out from the rest. She teaches other fitness professionals the science behind FASTer Way to Weight Loss®. She shows these newly certified coaches the ins and outs of her program and sets them on the path to building their own fitness businesses. Further demonstrating how Amanda Tress is empowering women in business, she will join us as a speaker at this year’s Brilliant event: Connect with Amanda and learn more about FASTer Way to Fat Loss®:

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Why we have too few women leaders | Sheryl Sandberg Facebook COO Sheryl Sandberg looks at why a smaller percentage of women than men reach the top of their professions — and offers 3 powerful pieces of advice to women aiming for the C-suite. TEDTalks is a daily video podcast of the best talks and performances from the TED Conference, where the world’s leading thinkers and doers give the talk of their lives in 18 minutes. TED stands for Technology, Entertainment, Design, and TEDTalks cover these topics as well as science, business, development and the arts. Closed captions and translated subtitles in a variety of languages are now available on, at Watch a highlight reel of the Top 10 TEDTalks at

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